Examinando por Materia "Virus del Zika"
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Publicación Acceso abierto Longitudinal extensive transverse myelitis and Zika virus: A diagnostic challenge in a hospital in Colombia(Sociedad Española de Neurología, 2019-01) Palacios, Eduardo; Clavijo Prado, C.; Ruiz, A.; Arias Antun, A.; Duran, E. JuliánZika virus is an arbovirus of the genus Flavivirus, which also includes the Japanese encephalitis, yellow fever, West Nile, and dengue viruses. Zika virus is spread by an arthropod, Aedes aegypti, and was first described in a population of rhesus monkeys in Uganda in 1947. Zika virus infection was described in humans in 1968, in Nigeria, when Zikaneutralising antibodies were isolated in a group of people presenting fever, skin rash, arthralgia, and conjunctivitis. The virus has since reached other parts of Africa and Asia. Since 2007, it has rapidly spread across several islands in the Pacific Ocean and various South American countries, including Brazil, French Guiana, and more recently Colombia. Zika virus infection causes a wide range of neurological complications, including longitudinally extensive transverse myelitisPublicación Acceso abierto Negative RT-PCR in a Newborn infected whit Zika virus : a case report(World Academy of Science, Engineering and Technology, 2019-06) Vallejo, Michael; Acuña Osorio, Edgar Mariano; Roa, Juan David; Peñuela, Rosa; Parra, Alejandra; Casallas, Daniela; Rodríguez, SheylaCongenital Zika Virus Syndrome is an entity composed by a variety of birth defects presented in newborns that have been exposed to the Zika Virus during pregnancy. The syndrome characteristic features are severe microcephaly, cerebral tissue abnormalities, ophthalmological abnormalities such as uveitis and chorioretinitis, arthrogryposis, clubfoot deformity and muscular tone abnormalities. The confirmatory test is the Reverse transcription polymerase chain reaction (RT-PCR) associated to the physical findings. Here we present the case of a newborn with microcephaly whose mother presented a confirmed Zika Virus infection during the third trimester of pregnancy, despite of the evident findings and the history of Zika infection the RT-PCR in amniotic and cerebrospinal fluid of the newborn was negative. RT-PCR has demonstrated a low sensibility in samples with low viral loads, reason why, we propose a clinical diagnosis in patients with clinical history of Zika Virus infection during pregnancy accompanied by evident clinical manifestations of the child.