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Use of Pulse Pressure Variation as Predictor of Fluid Responsiveness in Patients Ventilated With Low Tidal Volume: A Systematic Review and Meta-Analysis

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dc.contributor.authorAlvarado Sánchez, Jorge Iván
dc.contributor.authorCaicedo Ruiz, Juan Daniel
dc.contributor.authorDiaztagle Fernández, Juan José
dc.contributor.authorOspina-Tascón, Gustavo Adolfo
dc.contributor.authorCruz Martínez, Luis Eduardo
dc.date.accessioned2021-11-11T18:25:18Z
dc.date.available2021-11-11T18:25:18Z
dc.date.issued2020-01-24
dc.description.abstractIntroduction: Pulse pressure variation (PPV) has been shown to be useful to predict fluid responsiveness in patients ventilated at tidal volume (Vt) >8 mL kg−1. Nevertheless, most conditions in critical care force to use lower Vt. Thus, we sought to evaluate the operative performance of PPV when a Vt ⩽8 mL kg−1 is used during mechanical ventilation support. Methods: We searched PubMed and Embase databases for articles evaluating the operative performance of PPV as a predictor of fluid responsiveness in critical care and perioperative adult patients ventilated with tidal volume ⩽8 mL kg−1 without respiratory effort and arrhythmias, between January 1990 and January 2019. We included cohort and cross-sectional studies. Two authors performed an Independently selection using predefined terms of search. The fitted data of sensitivity, specificity, and area under the curve (AUC) were assessed by bivariate and hierarchical analyses. Results: We retrieved 19 trials with a total of 777 patients and a total of 935 fluid challenges. The fitted sensitivity of PPV to predict fluid responsiveness during mechanical ventilation at Vt ⩽8 mL kg−1 was 0.65 (95% confidence interval [CI]: 0.57-0.73), the specificity was 0.79 (95% CI: 0.73-0.84), and the AUC was 0.75. The diagnostic odds ratio was 5.5 (95% CI: 3.08-10.01, P < .001) by the random-effects model. Conclusions: Pulse pressure variation shows a fair operative performance as a predictor of fluid responsiveness in critical care and perioperative patients ventilated with a tidal volume ⩽8 mL kg−1 without respiratory effort and arrhythmias.eng
dc.format.extent10 p.spa
dc.format.mimetypeapplication/pdfspa
dc.identifier.urihttps://repositorio.fucsalud.edu.co/handle/001/1902
dc.language.isoengspa
dc.publisherThousand Oaks CA: SAGE Publicationsspa
dc.publisher.placeEstados Unidosspa
dc.relation.citationendpage10spa
dc.relation.citationstartpage1spa
dc.relation.citationvolume14spa
dc.relation.ispartofClinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine ISSN:1179-5484 Vol.14 Mes.12 (2020)
dc.relation.ispartofjournalClinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicinespa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_abf2spa
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.sourcehttps://journals.sagepub.com/doi/full/10.1177/1179548420901518spa
dc.subject.decsCuidados críticos
dc.subject.decsHemodinámica
dc.subject.decsAtención perioperativa
dc.subject.decsPresión sanguínea
dc.subject.decsVolumen de ventilación pulmonar
dc.subject.proposalCritical careeng
dc.subject.proposalHemodynamiceng
dc.subject.proposalPerioperative careeng
dc.subject.proposalPulse pressureeng
dc.subject.proposalSepsiseng
dc.subject.proposalTidal volumeeng
dc.titleUse of Pulse Pressure Variation as Predictor of Fluid Responsiveness in Patients Ventilated With Low Tidal Volume: A Systematic Review and Meta-Analysiseng
dc.typeArtículo de revistaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.redcolhttps://purl.org/redcol/resource_type/WPspa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
dspace.entity.typePublication

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