Envíos recientes

Cobertura de vacunación contra COVID-19 por esquema en Colombia

Díaz Pinzón, Jorge Enrique | 2021-03-08

Colchicine: A potential therapeutic tool against COVID-19. Experience of 5 patients

Montealegre Gómez, Giovanni | 2020-05-16

COVID-19 is a newly emerged disease that has become a global public health challenge. Due to a lack of knowledge about the virus, a significant number of potential targets for using a particular drug have been proposed. Five cases with a clinical history of biopolymers in the gluteal region that developed iatrogenic allogenosis (IA) are presented here. The 5 cases were put under colchicine treatment for IA crisis and had non-specific symptoms (headache, cough without dyspnea, and arthralgias) with a positive SARSCoV-2 test. Their close contacts had mild to severe symptoms and three of them died. In the SARS-CoV-2 infection different inflammatory pathways are altered where colchicine reduces cytokine levels as well as the activation of macrophages, neutrophils, and the inflammasome. The possible mechanisms that colchicine may use to prevent acute respiratory distress syndrome (ARDS) in patients with COVID-19 infection are also reviewed in this article.

Contagios, recuperados y fallecidos por SARS-COV-2 quinientos días después del primer reporte en Colombia

Díaz Pinzón, Jorge Enrique | 2021-03-08

Convalescent plasma in Covid-19: Possible mechanisms of action

Rojas, Manuel | 2020-07

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible of the coronavirus disease 2019(COVID-19) pandemic. Therapeutic options including antimalarials, antivirals, and vaccines are under study.Meanwhile the current pandemic has called attention over old therapeutic tools to treat infectious diseases.Convalescent plasma (CP) constitutes thefirst option in the current situation, since it has been successfully usedin other coronaviruses outbreaks. Herein, we discuss the possible mechanisms of action of CP and their re-percussion in COVID-19 pathogenesis, including direct neutralization of the virus, control of an overactiveimmune system (i.e., cytokine storm, Th1/Th17 ratio, complement activation) and immunomodulation of ahypercoagulable state. All these benefits of CP are expected to be better achieved if used in non-criticallyhospitalized patients, in the hope of reducing morbidity and mortality.

Desarrollo de una máscara de bajo costo para prevenir la propagación de aerosoles en endoscopia endonasal en la base del cráneo durante la pandemia del COVID-19

Abdala Vargas, Nadin | 2021-03-08

Dosis aplicadas contra COVID-19 por laboratorio en las entidades territoriales de Colombia

Díaz Pinzón, Jorge Enrique | 2021-03-08

Esquemas completos aplicados contra COVID-19 priorizados por entidad territorial en Colombia

Díaz Pinzón, Jorge Enrique | 2021-03-08

Impacto del suministro de vacunas contra COVID-19 sobre la letalidad por SARS-COV-2 en Colombia

Díaz Pinzón, Jorge Enrique | 2021-03-08

Letalidad por SARS-COV-2 a nivel mundial

Díaz Pinzón, Jorge Enrique | 2021-03-08

Observación del plan de vacunación del COVID-19 en Colombia

Díaz Pinzón, Jorge Enrique | 2021-03-08

Proporción de personas vacunadas contra COVID-19 a nivel mundial

Díaz Pinzón, Jorge Enrique | 2021-03-08

Vacunas asignadas y aplicadas contra COVID-19 por entidad territorial en Colombia

Díaz Pinzón, Jorge Enrique | 2021-03-08

Vacunas contra COVID-19 aplicadas por grupo de edad en Colombia

Díaz Pinzón, Jorge Enrique | 2021-03-08