Parra Medina, RafaelLópez Correa, PatriciaGutiérrez, VíctorPolo, José Fernando2022-09-22A 43-year-old man presented with two-month history of fatigue, weakness, paleness, rectal bleeding, sweating, and weight loss of 10 kg in the past one month. A complete blood count revealed anaemia. The patient underwent a right hemicolectomy. The microscopic examination revealed an adenosquamous carcinoma associated with a mucinous adenocarcinoma in a patient with microsatellite instability due to loss of MLH1 and PMS2 expression and retention of MSH2 and MSH6 expression in both the squamous and glandular components. We also observed an atypical immunohistochemical phenotype in the adenocarcinoma component showing CK7 expression and reduced CK20 and CDX2 expression20184 p.application/pdfArtículo de revista2022-09-220126-8635https://repositorio.fucsalud.edu.co/handle/001/3168enginfo:eu-repo/semantics/openAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)Adenosquamous carcinomaMucinous adenocarcinomasMicrosatellite instabilityAdenocarcinomaAdenocarcinoma mucinosoInestabilidad de microsatéliteshttp://purl.org/coar/access_right/c_abf2