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A systematic literature review of the management of chronic venous ulcers with autologous fibrin matrix with or without growth factors

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dc.contributor.authorGarcía Botero, Alejandra
dc.contributor.authorCantini Ardila, Jorge Ernesto
dc.contributor.authorDevoz Borja, Luis David
dc.contributor.authorGómez-Ortega, Viviana
dc.date.accessioned2021-02-10T17:48:59Z
dc.date.available2021-02-10T17:48:59Z
dc.date.issued2018-04-23
dc.description8 p.eng
dc.description.abstractAim: To evaluate available evidence for the effective management of venous leg ulcers with fibrin matrix with or without growth factors. Methods: A systematic review of the literature was performed to evaluate the use of fibrin matrices with or without growth factors for the management of chronic venous ulcers in lower limbs. Article searches were performed in MEDLINE, EMBASE, COCHRANE, LILACS and ongoing clinical trials at ClinicalTrial.gov. Results: The search in MEDLINE and EMBASE identified three articles; one was a pilot study evaluating the use of fibrin matrix and autologous growth factors that included patients with chronic ulcers of different etiology. The second article was a description of the product used in the previous study, and the third consisted of a series case reports of patient treated with cultured keratinocytes in a fibrin matrix. A COCHRANE searched resulted in one study assessing the cost effectiveness of using different fibrin matrices. The search in ClinicalTrial.gov and LILACS did not result in any findings. Conclusion: The study did not provide a conclusive evidence for the use of fibrin matrices in patients with venous leg ulcers.eng
dc.format.mimetypeapplication/pdfspa
dc.identifier.doittp://dx.doi.org/10.20517/2347-9264.2018.09.
dc.identifier.other
dc.identifier.urihttps://repositorio.fucsalud.edu.co/handle/001/1338
dc.language.isoengspa
dc.relation.citationendpage8spa
dc.relation.citationissue15spa
dc.relation.citationstartpage1spa
dc.relation.citationvolume5spa
dc.relation.citesGarcía Botero, A, Cantini Ardila, J, Devoz Borja, L y Gómez-Ortega, V. (2018-04-23.). A systematic literature review of the management of chronic venous ulcers with autologous fibrin matrix with or without growth factors.
dc.relation.ispartofjournalPlastic and Aesthetic Researchspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.coarhttp://purl.org/coar/access_right/c_14cbspa
dc.rights.creativecommonsAtribución 4.0 Internacional (CC BY 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/spa
dc.sourcehttps://parjournal.net/article/view/2491spa
dc.subject.decsÚlcera varicosa
dc.subject.decsPéptidos y proteínas de señalización intercelular
dc.subject.decsPierna
dc.subject.decsLiteratura de revisión
dc.subject.proposalVenous ulcerseng
dc.subject.proposalGrowth factorseng
dc.subject.proposalFibrin matrixeng
dc.subject.proposalLegseng
dc.titleA systematic literature review of the management of chronic venous ulcers with autologous fibrin matrix with or without growth factorseng
dc.typeArtículo de revistaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.coarversionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
dspace.entity.typePublication

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